Dear Colleagues, The 8th International Conference on Systems Biology and the 4th Translational Bioinformatics Conference (ISB/TBC 2014), organized by Chinese Academy of Sciences and Qingdao University will be held in Qingdao, China, October 25-27, 2014. The conference is sponsored by National Natural Science Foundation of China (NSFC), Academy of Mathematics and Systems Sciences of CAS (AMSS), Shanghai Institutes for Biological Sciences of CAS (SIBS), Qingdao Institute of Bioenergy and Bioprocess Technology of CAS (QIBEBT), Qingdao University, Computational Systems Biology Society of ORSC, Systems Biology Technical Committee of IEEE SMC Society, Korean Society for Bioinformatics and Systems Biology (KSBSB), The Korean Society of Medical Informatics (KOSMI), Korean Genome Organization (KOGO). The papers presented at the conference will be published on the IEEE Xplore, and submitted to EI Compendex for consideration for indexing. The selected papers are going to be published on the special issues of SCI indexed journals such as JAMIA (J Am Med Inform Assoc), METHODS, BMC Medical Genomics,IET Systems Biology, BioData Mining, Healthcare Informatics Research. For more information, please visit the conference website at: http://www.aporc.org/ISB/2014/ Wish you a happy Chinese New Year! ISB/TBC 2014 Organizing Committee