Dear List not a long while ago we discussed a case of syncope. Now the part II. this Cadet underwent a hypoxia indoctrination run prior to beginning his basic flying this term. Had a brief episode of Loss of Consciousness (LOC) at 30,000 Ft without oxygen, regained instant consciousness with 100% oxygen. A repeat run, similar profile next day, he remained event free. he had an earlier run as well last year, remained event free. He had flown 09 dual sorties without any symptoms this term after the hypoxia indoctrination run. Earlier term had done 14 sorties. Had gone for his review, had another hypoxia evaluation run at 30,000 ft and had LOC, regained with 100% oxygen. Now he is permanently A4G1 for Vasovagal Syncope (VVS). Without doubting the disposal, I still have certain lingering doubts: (1) Is the endurance training at Academies, with emphasis on cross country run and similar efforts leading to bradycardia responsible for his episodes of VVS? (2) at 30,000 ft he is already 10,000 ft above the Critical stage of hypoxia, where LOC is an end point. Does a stress induced LOC qualify for final determination of permanent A4? Consider, any one of us exposed to 30 K may have similar event except the time frame may vary. (3) If VVS is due to neural mediation leading to peripheral vasodilatation and bradycardia and final LOC, do we not need to repeat the complete cardiac evaluation to find any incipient cause of bradycardia or ??asystole leading to LOC under various stresses, not just hypoxia alone. Esp. with tilt table test being the closest gold standard, should it not be repeated with on-line BP and Pulse monitoring, with EEG thrown in, if possible? (4) Why not an EP study as well? (5) Where does a pilot get exposed to 30,000 ft equivalent of Hypoxia in actual situation. Fighters - only in cruise and with defective Oxygen system on board. Tpt - Dornier ceiling is 11-12,000 Ft (Compensatory stage); other ac are all pressurised. Helicopters - only glacier operations may border between 15,000 to 22,000 Ft, ranging between stage of disturbance and critical. So does hypoxia induced LOC alone be the deciding factor in such a case? For the information of the List: (a) all his previous cardio-neuro evaluations were normal. (b) Most importantly, the Cadet has gracefully accepted the outcome, and is applying for change of branch. May I request the List to comment on the pertinent issues for the sake of academic interest in this case. with warm wishes Sanjiv