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Dagens #fsvoversigt:
Associations of sugar-sweetened and artificially sweetened soda with chronic
kidney disease: a systematic review and meta-analysis.
Nephrology (Carlton). 2014 Dec;19(12):791-7
Authors: Cheungpasitporn W, Thongprayoon C, O'Corragain OA, Edmonds PJ,
Kittanamongkolchai W, Erickson SB
Abstract
BACKGROUND/OBJECTIVES: The risk of chronic kidney disease (CKD) in patients who
regularly drink soda is controversial. The objective of this meta-analysis was
to evaluate the associations between consumption of sugar-sweetened and
artificially sweetened soda and CKD.
METHODS: A literature search was performed using MEDLINE, EMBASE and the
Cochrane Database of Systematic Reviews from inception until 30 June 2014.
Studies that reported odds ratios or hazard ratios comparing the risk of CKD in
patients consuming significant amounts of either sugar-sweetened or
artificially sweetened soda versus those who did not consume soda were
included. Pooled risk ratios (RR) and 95% confidence intervals (CI) were
calculated using a random-effects, generic inverse variance method.
RESULTS: Five studies were included in our analysis of the association between
consumption of sugar-sweetened soda and CKD. The pooled RR of CKD in patients
consuming sugar-sweetened soda was 1.58 (95% CI 1.00-2.49). Four studies were
selected to assess the association between consumption of artificially
sweetened soda and CKD. The pooled RR of CKD in patients consuming artificially
sweetened soda was 1.33 (95% CI 0.82-2.15).
CONCLUSIONS: Our study demonstrates statistically significant increased risks
of CKD in patients consuming sugar-sweetened soda, but not in patients
consuming artificially sweetened soda. This finding suggests that
sugar-sweetened soda consumption is associated with CKD and may impact clinical
management and primary prevention of CKD in high-risk patients.
PMID: 25251417 [PubMed - indexed for MEDLINE]
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Dette abstract er hentet via PubMed fra National Library of Medicine, USA
(http://www.ncbi.nlm.nih.gov/About/disclaimer.html).
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Se abstractet i PubMed: http://evidens.link/1O88Xyz
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