[ceevol] Final reminder: CEE Seminar today: Title: Population genomics and complex traits in yeast
- From: "Dempster, Jane" <j.dempster@xxxxxxxxx>
- To: "Dempster, Jane" <j.dempster@xxxxxxxxx>
- Date: Wed, 11 Jan 2012 11:26:44 +0000
For GEE & CEE Members (with apologies for cross-posting)
Dear Colleagues
A final reminder regarding today’s CEE Seminar, to be hosted by Dan Jeffares.
Best wishes
Jane
From: Dempster, Jane
Sent: 09 January 2012 17:33
To: 'Jane Dempster'
Subject: GEE & CEE Seminars this week
Dear Colleagues
Weds 11 Jan
17:00 – 18:30
Venue: A V Hill LT
Speaker: Gianni LITI, CNRS, Nice, website:
http://ircan.org/index.php?option=com_content&view=article&id=72&Itemid=98
Title: Population genomics and complex traits in yeast
Natural variation offers a powerful approach for assigning function to DNA
sequence-a pressing challenge in the age of high throughput sequencing
technologies. In the past decade, S. cerevisiae has emerged as a powerful model
for linkage analysis. This success is largely due to its intrinsic biological
features. However, yeast forward genetics studies mostly used common laboratory
strains sampling a very limited fraction of the species variation. In the past
ten years, we have assembled a large collection of Saccharomycesstrains and
characterised this set of strains at the genetic, genomic and phenotypic
levels. We also generated a large collection of recombinant strains that
represent a powerful tool to identify sequence variants underpinning phenotypic
variation. These recombinants were generated from a selection of founder
strains that capture the majority of the genetic and phenotypic variation of
the species. We used both linkage and association (restricted to candidate
genes) to identify the quantitative trait loci (QTLs) underlying complex
traits. In addition to the classical F1 segregants originated from an hybrid
obtained by crossing two parents, we explored different breeding strategies to
generate artificial populations ideal for QTL mapping. Here, I present the
advantages of these new methods together with a new approach to accurately map
trait loci using artificial selection. Together these strain sets and methods
provide a comprehensive resource for the research community for genetic and
phenotypic analysis and can be applied to other genetic systems.
Fri 13 Jan
16:00 – 17:00, followed by drinks
Speaker: Sam Tazzyman:
http://www.ucl.ac.uk/complex/research/fellowships/tazzyman
Title: Why big is beautiful in sexual selection
Venue: Darwin Biochemstry LT
(map<http://maps.google.com/maps?hl=en-GB&q=Darwin%20Biochemstry%20LT>)
more
details»<http://www.google.com/calendar/event?eid=YjMzZWp2amliYzI5bGcybjk0ZTUxcnYxZWMga2F0aXBvLm9yZ19ybWo0aWxhaDl1NDEzYXJ2aWlta2tsM2xlY0Bn&ctz=Europe/London>
copy to my
calendar<https://www.google.com/calendar/event?action=TEMPLATE&hl=en_GB&text=Sam%20Tazzyman%3A%20Why%20big%20is%20beautiful%20in%20sexual%20selection.&dates=20120113T160000%2F20120113T170000&location=Darwin%20Biochemstry%20LT&ctz=Europe%2FLondon&details>
(Google)
All are welcome! Please join us.
Best wishes
Jane
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