Pam, landscape simply means that the text is placed sideways on the scanner bed which is most often the way it works out when scanning in two-page mode. Portrait means that the top of the page is at the top of the scanner bed. In the final analysis, I don't know that it makes a great deal of difference which option is checked because there is another option checked that tells it to automatically adjust for page orientation. It may save a nanna-second to have it consistent with what you intend to do. And Kellie, thanks for saving this post. I'm saving it, too, but back-up is definitely appreciated! Peace and Hope, Donna