Please see below for three ancillary meetings at SOT my organization is
co-sponsoring with other ASCCT members. Please feel free to forward widely.
Hands-On Seminar: Creating an Adverse Outcome Pathway in the AOP Wiki
Tuesday, March 14
Hyatt Regency Baltimore
Constellation Ballroom A
The Human Toxicology Project Consortium and the Physicians Committee for
Responsible Medicine invite you to deepen your understanding of the AOP Wiki
and gain experience entering an Adverse Outcome Pathway in a structured,
hands-on seminar Tuesday evening.
Version 2.0 of the AOP Wiki was released in November 2016, and this seminar
will be ideal for those wishing to gain some hands-on experience with the new
version as well as those who are new to the AOP concept.
The HTPC will present a new online course on AOPs, and course attendees will
work through a case example in small groups.
Please register to ksullivan@xxxxxxxx<mailto:ksullivan@xxxxxxxx>.
Driving Innovation in Preclinical Pharma Testing: Takeaways and Opportunities
Following the 2017 Preclinical Innovation and Patient Safety Roundtable
Wednesday, March 15
Room Tubman A
DiscoverX and the Physicians Committee for Responsible Medicine invite you to
join us for breakfast and discussion on improving preclinical testing through
scientific innovation, regulatory updates and training.
On January 11, 2017, stakeholders from federal agencies, the pharmaceutical
industry, academia, health, research and patient organizations, and technology
companies attended the Preclinical Innovation and Patient Safety Roundtable to
discuss scientific, legal and training issues that stifle preclinical
innovation and negatively affect patients. This meeting will highlight key
takeaways and recommendations for next steps.
Please RSVP to ebaker@xxxxxxxx<mailto:ebaker@xxxxxxxx>.
Alternative Approaches to Systemic and Topical Toxicity: Making Progress on the
EPA OPP Six-Pack
Wednesday, March 15
Sheraton Inner Harbor
Loch Raven room
This open stakeholder discussion will feature presentations and discussions
highlighting work to reduce and replace in vivo testing for the “six-pack”, a
set of six acute systemic and topical toxicity tests required by the EPA Office
of Pesticide Programs for pesticide active ingredients and formulations. These
tests include: acute oral, dermal, and inhalation toxicity, skin and eye
irritation, and skin sensitization.
The evening will focus on two specific elements of this ongoing work: 1) a
pilot effort to reduce formulation testing using the GHS Additivity Equation
for acute systemic toxicity, and 2) in vitro methods for skin and eye
irritation. Ongoing work to provide predictive analysis of the in vitro methods
and necessary next steps will be discussed.
The participation of all stakeholders wishing to learn more or get involved is