[ascct] Post-doc available
- From: Kristie Sullivan <KSullivan@xxxxxxxx>
- To: "ascct@xxxxxxxxxxxxx" <ascct@xxxxxxxxxxxxx>
- Date: Wed, 16 Apr 2014 12:44:27 -0400
Postdoctoral Fellowship - Center for Human Health Assessment
The Hamner Institutes for Health Sciences is seeking a Postdoctoral Candidate
to participate in the development of computational models of human exposure to
environmental compounds, coupling probabilistic descriptions of environmental
exposure pathways with physiologically based pharmacokinetic (PBPK) models of
absorption, distribution, metabolism and excretion. This is a post-doctoral
fellow position with a possibility of promotion to a research scientist.
The ultimate goal of this research is to develop an integrated modeling
platform linking exposures to internal dose and potential for health effects.
The modeling platform will be designed to support (1) estimation of internal
exposures resulting from complex, time-variant near-field exposures to
chemicals in specific micro-environments, including the home; (2) estimation of
likely exposures based on human biomonitoring data that can be used to evaluate
and refine approaches for conducting traditional exposure pathway modeling; (3)
description of human variability based on both exposure and pharmacokinetics.
Two major application areas of interest are 1) linking quantitative
descriptions of environmental exposure and resulting target tissue dose to
pharmacodynamic modeling of adverse outcome pathways and 2) interpreting
epidemiological findings on chemical-health effects associations.
This position entails the development and application of kinetic and
statistical models that incorporate data from a variety of fields including
physiology, biology, pharmacokinetics, toxicology, and exposure
characterization to simulate chemical biomarkers in humans at the population
level. The ideal candidate will have a Ph.D. in engineering or a quantitative
scientific field preferably with experience in exposure modeling. Candidates
with Ph.D.’s in disciplines such as bioengineering, toxicology, pharmacology,
and physiology with a strong computational background are especially encouraged
to apply. Experience in the interpretation of experimental results from
epidemiology, toxicity, metabolism, and pharmacokinetic studies, and in the use
of the results in computational modeling will be advantageous.
Experience with at least one programming or scripting language is required
including R, Java, Perl, Python, C, ACSLX, and/or MATLAB. Excellent
communication skills and the ability to work independently but also as part of
a team will be essential. The successful candidate will be expected to work
closely with Hamner scientists currently conducting research on PBPK modeling
to create an integrated probabilistic exposure-PBPK modeling platform.
Candidates will also be expected to maintain a strong collaborative
relationship with EPA epidemiologists, exposure scientists and PBPK modelers in
the RTP area.
How to Apply
Qualified candidates need to submit their resume and Postdoctoral application,
which can be found at http://www.thehamner.org/careers/application-forms/, to
koverman@xxxxxxxxxxxxx<mailto:koverman@xxxxxxxxxxxxx> or fax to 919-558-1430.
Please refer to the "Postdoc in CHHA" position. “Equal Opportunity /
Affirmative Action Employer – m/f/d/v”
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- » [ascct] Post-doc available - Kristie Sullivan
