[ascct] New/Revised OECD test guidelines published

  • From: Kristie Sullivan <KSullivan@xxxxxxxx>
  • To: "ascct@xxxxxxxxxxxxx" <ascct@xxxxxxxxxxxxx>
  • Date: Fri, 23 Sep 2016 17:12:38 -0400

The OECD has published the following new Test Guidelines:

o   Test No. 
458<http://www.oecd-ilibrary.org/docserver/download/9716131e.pdf?expires=1473934550&id=id&accname=guest&checksum=612ADC288DFF4A7DF0CD42157FCA2B11>:
 Stably Transfected Human Androgen Receptor Transcriptional Activation Assay 
for Detection of Androgenic Agonist and Antagonist Activity of Chemicals
o   Test No. 442E: In Vitro Skin 
Sensitisation<http://www.oecd-ilibrary.org/environment/test-no-442e-in-vitro-skin-sensitisation_9789264264359-en>

The OECD also published several updated versions of existing Test Guidelines, 
including:

o   Test No. 431: In vitro skin corrosion: reconstructed human epidermis (RHE) 
test 
method<http://www.oecd-ilibrary.org/environment/test-no-431-in-vitro-skin-corrosion-reconstructed-human-epidermis-rhe-test-method_9789264264618-en>
o   Test No. 455: Performance-Based Test Guideline for Stably Transfected 
Transactivation In Vitro Assays to Detect Estrogen Receptor Agonists and 
Antagonists<http://www.oecd-ilibrary.org/environment/test-no-455-performance-based-test-guideline-for-stably-transfected-transactivation-in-vitro-assays-to-detect-estrogen-receptor-agonists-and-antagonists_9789264265295-en>
o   Test No. 473: In Vitro Mammalian Chromosomal Aberration 
Test<http://www.oecd-ilibrary.org/environment/test-no-473-in-vitro-mammalian-chromosomal-aberration-test_9789264264649-en>
o   Test No. 476: In Vitro Mammalian Cell Gene Mutation Tests using the Hprt 
and xprt 
genes<http://www.oecd-ilibrary.org/environment/test-no-476-in-vitro-mammalian-cell-gene-mutation-tests-using-the-hprt-and-xprt-genes_9789264264809-en>
o   Test No. 487: In Vitro Mammalian Cell Micronucleus 
Test<http://www.oecd-ilibrary.org/environment/test-no-487-in-vitro-mammalian-cell-micronucleus-test_9789264264861-en>
o   Test No. 489: In Vivo Mammalian Alkaline Comet 
Assay<http://www.oecd-ilibrary.org/environment/test-no-489-in-vivo-mammalian-alkaline-comet-assay_9789264264885-en>
o   Test No. 490: In Vitro Mammalian Cell Gene Mutation Tests Using the 
Thymidine Kinase 
Gene<http://www.oecd-ilibrary.org/environment/test-no-490-in-vitro-mammalian-cell-gene-mutation-tests-using-the-thymidine-kinase-gene_9789264264908-en>

All OECD Test Guidelines, as well as more information about the Test Guidelines 
Programme, can be found by following the links on this page: 
http://www.oecd.org/chemicalsafety/testing/oecd-guidelines-testing-chemicals-related-documents.htm.



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