[ascct] NC3Rs 2013 CRACK IT Challenges Launch event 5 September 2013

  • From: Kristie Sullivan <KSullivan@xxxxxxxx>
  • To: "ascct@xxxxxxxxxxxxx" <ascct@xxxxxxxxxxxxx>
  • Date: Fri, 26 Jul 2013 15:08:58 -0400

Dear Colleagues:

The NC3Rs public-private partnership "CRACK IT Challenges" for the upcoming 
year have been announced. There will be a launch and networking event on the 
5th of September.

The awards are open to non-UK-based applicants but the project leader must be 
UK-based. Each of the challenges offers up to 1 Million GBP, so if you have 
collaborators in the UK you may wish to put an application together.

Questions can be directed to 
CRACKITenquiries@xxxxxxxxxxxx<mailto:CRACKITenquiries@xxxxxxxxxxxx>.

Kristie Sullivan
Secretary, ASCCT
www.ascctox.org<http://www.ascctox.org>


We are pleased to announce this year’s NC3Rs CRACK IT Challenges 2013 launch 
event will take place on 5 September in Central London.

CRACK IT Challenges is a research competition to solve scientific and business 
problems identified by the bioscience sector. The Challenges are designed to 
reduce the reliance on animal models and/or improve animal welfare and lead to 
the development of marketable products. The competition is run with the SBRI 
and Challenges are sponsored by companies who provide in-kind contributions 
such as data, validation and expertise.

This year’s competition includes five Challenges, involving seven sponsors:

§  UnTangle: Development of an iPSC cell neuronal network platform to assay tau 
spread and pathology for Alzheimer’s Disease drug development.

§  InPulse: iPSC cardiomyocyte platform to assess drug-induced contractility 
liabilities.

§  Inhalation Translation: Development of an approach to non-invasively assess 
inflammation and adverse events in rodent models of respiratory disease.

§  NephroTube: Development of a multi-compartmental, microfluidic tissue model 
of tubular injury in assays of nephrotoxicity.

§  Virtual Lab: Use of virtual information and tools to enhance disease 
modelling and new target development.

Each of these Challenges offers up to one million GBP funding and a research 
contract for up to three years. The Challenge briefs will be available on the 
CRACK IT and SBRI website from 1 August 2013.

The launch event is free to attend but registration is essential. You must 
first register on the CRACK IT 
website<http://www.crackit.org.uk/calendar/2013launchevent?utm_source=crack+it+email+out&utm_medium=email&utm_campaign=crack+it+2013+launch+email+out>
 and then for the event itself. Event registration will open at the beginning 
of August.

The programme for the event includes:

§  Challenge-specific surgeries where participants can meet the sponsors and 
discuss the Challenges in detail

§  Networking sessions around Challenge zones providing an opportunity to 
identify new collaborators to help solve the Challenges

§  A case study of the CRACK IT Challenges experience from a winner of one of 
the 2011 CRACK IT Challenges



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