[ascct] NAFTA working group publishes QSAR guidance
- From: Kristie Sullivan <KSullivan@xxxxxxxx>
- To: "ascct@xxxxxxxxxxxxx" <ascct@xxxxxxxxxxxxx>
- Date: Fri, 30 Nov 2012 13:50:53 -0500
NAFTA TWG Quantitative Structure Activity Relationships [(Q)SAR] Guidance
Document
The U.S. Environmental Protection Agency Office of Pesticide Programs (U.S.
EPA/OPP) and Health Canada’s Pest Management Regulatory Agency (PMRA) have
cooperated on the development of a guidance document on the use of Quantitative
Structure Activity Relationships [(Q)SAR] for pesticide risk assessors. This
document has been developed under a North American Free Trade Agreement
Technical Working Group (NAFTA TWG) project, 21st Century Toxicology:
Integrated Approaches to Testing and Assessment.
The NAFTA TWG (Q)SAR Guidance Document provides an introduction to (Q)SAR and a
flexible framework to assist with problem formulation for (Q)SAR, assessing the
adequacy of predictions, and incorporating predictions into weight of evidence
based assessments of pesticides. While the (Q)SAR Guidance Document was not
designed to be a step-by-step manual, it provides useful guidance to evaluators
who are reviewing predictions included in pesticide submissions or who are
using (Q)SAR to help identify additional data requirements for pesticides,
metabolites or degradates. Moreover, it also supplements, but does not replace,
existing (Q)SAR guidance documents from the Organisation for Economic
Cooperation and Development (OECD), the European Chemicals Bureau and other
agencies.
The NAFTA TWG (Q)SAR Guidance Document is currently available for download at
http://www.epa.gov/oppfead1/international/naftatwg/guidance/qsar-guidance.pdf.
Kristie Sullivan
Secretary, ASCCT
www.ascctox.org<http://www.ascctox.org>
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