[ascct] Fwd: You are Invited to a Collaborative Webinar Discussion on Overcoming Drug Discovery Biases with Drs. Lipinski, Soellner, and Bunin

  • From: Kristie Sullivan <KSullivan@xxxxxxxx>
  • To: "ascct@xxxxxxxxxxxxx" <ascct@xxxxxxxxxxxxx>
  • Date: Wed, 24 Sep 2014 12:50:53 -0400

See below for another webinar that may be of interest from Collaborative Drug 
Discovery; see link for registration and other information.

Entropic and Enthalpic Propensities Inherent in Structure Based Drug Discovery 
(SBDD) and High Throughput Screening (HTS) with:

 *   Dr. Christopher Lipinski
 *   Dr. Matthew Soellner
 *   Dr. Barry Bunin

Online Webinar:  Wed, Oct 22 from 2-3pm ET (11-noon PT, 6-7pm GMT)



Christopher Lipinski's decades of experience practicing medicinal chemistry for 
Pfizer and post-Pfizer have led him to believe that there are inherent biases 
in the molecules developed via different drug discovery approaches.   During 
this thought-provoking webinar, we will expound on how thermodynamic 
considerations influence lead optimization and the implications for the 
scientific community.   Matthew Soellner (Chemical Biology Professor) and CDD 
(CDD's CEO Barry Bunin with CDD's Collaborations Director Nadia Litterman) will 
follow with new empirical evidence from the extensive public activity data 
contained in CDD Vault.  By comparing physical properties with experimentally 
measured activities across a range of small molecules and protein targets, they 
will reveal trends in the contributions of enthalpic and entropic terms. We 
will further demonstrate, using CDD Vault Calculations, how to compensate for 
these natural biases, with real world implications for affinity and selectivity 
optimization.



Please Register 
Here<http://r20.rs6.net/tn.jsp?f=0017bL4nVYUYvlkbSqefXaUmPupalXuK8Y7y3NPPnCHIr-EkBP9i0SsLdDtrroARWq9H5cprry_yJcP0BagSmV_x0JjBCFSWuwRXR5pJtSLz5wW2unozULq9WF-PHVQ2JICnNSDb9bk4dCLQxoyXA8tmYaCyX-O_R2Q_0HdnVMqV12iS21tpxpy1YRoUp_Gg0xeq_MuP9scH5NdgwZXkntKwgVUuaEVl5wFQQ8zdJcX4RYoV4_l05Gc9w==&c=Vl_-3wtfbC5o2i9G13Oxh2oBrGJpyuiAirpov_YLpSV0ohzWcy3s5g==&ch=siiG3DgSv9n1buU4P7GkFUB5rkscCa2Ceq0bH204kP3j8v6AsHgNwQ==>
 to reserve your place at this live event - it will be a unique opportunity to 
join the discussion about these fundamental questions of probe and drug 
discovery.

Best,
-Barry
P.S.   You can learn more about the event on our 
blog<http://r20.rs6.net/tn.jsp?f=0017bL4nVYUYvlkbSqefXaUmPupalXuK8Y7y3NPPnCHIr-EkBP9i0SsLdDtrroARWq9LOXXi-QSzcMgZhCBL8tRnYDitwtGvpvQR9w9vi2Ni0djn1ewosWoqN7lQR36uz5Wr-cmbtJh1O5yo5ckSUNlPY2gDpW4wyLVzgBXXTSUU-qTJa8GKVZPN1lnfDNxQV_4JrCzqGOeLF7Iw6j-9L6k_X4d00CU_VlmZHuX-IXwd9ZWjePr5aQ-IviGOMabeszJP9CRwjwsFGP8SWPikneoP-9m9_WAI3eT5tuRQtAOsT4h2P3r8lxoahspTNx1d0tv5WcHDCJJvUB8LT7xbBWbl9h_L5gi0eSQ&c=Vl_-3wtfbC5o2i9G13Oxh2oBrGJpyuiAirpov_YLpSV0ohzWcy3s5g==&ch=siiG3DgSv9n1buU4P7GkFUB5rkscCa2Ceq0bH204kP3j8v6AsHgNwQ==>.







Barry A. Bunin, PhD,
CEO
Collaborative Drug Discovery (CDD), Inc.,
CDD 
Vault<http://r20.rs6.net/tn.jsp?f=0017bL4nVYUYvlkbSqefXaUmPupalXuK8Y7y3NPPnCHIr-EkBP9i0SsLcoelTnq6gQprZPZzXrr2GKScBula7IXHOuxfwE__JhVcD9LkC9tXjbdOX0_HLkOAU4EnN3aioVLsMijX-dcnV_67Pa5LB2aIRbhpf1C4Rrgvo1djWaJW6fTBblQz5dyHdtHTf3RrtxsQSfuJvuoEzjcQj4sxMs51A==&c=Vl_-3wtfbC5o2i9G13Oxh2oBrGJpyuiAirpov_YLpSV0ohzWcy3s5g==&ch=siiG3DgSv9n1buU4P7GkFUB5rkscCa2Ceq0bH204kP3j8v6AsHgNwQ==>
Tel: (650) 204-3084
Email: info@xxxxxxxxxxxxxxxxxxxxx
Web: 
www.collaborativedrug.com<http://r20.rs6.net/tn.jsp?f=0017bL4nVYUYvlkbSqefXaUmPupalXuK8Y7y3NPPnCHIr-EkBP9i0SsLXowESptQsouqbd-AvaFJMqW4iT3FWl-znIShaMOByN55HRu_f-aIeQtgLoCj7fqLpWFo6c8hDRLg97v-tj14BBj405xXylHc1HIDBxLKxjlRZkZ3_jY6Iw7lpNbOCnBLWRLsdbiUCIs&c=Vl_-3wtfbC5o2i9G13Oxh2oBrGJpyuiAirpov_YLpSV0ohzWcy3s5g==&ch=siiG3DgSv9n1buU4P7GkFUB5rkscCa2Ceq0bH204kP3j8v6AsHgNwQ==>
 "Archive, Mine, Collaborate"















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  • » [ascct] Fwd: You are Invited to a Collaborative Webinar Discussion on Overcoming Drug Discovery Biases with Drs. Lipinski, Soellner, and Bunin - Kristie Sullivan