Upcoming meeting that might be of interest: Kristie Sullivan, MPH Secretary American Society for Cellular and Computational Toxicology www.ascctox.org<http://www.ascctox.org> To view this email as a web page, go here.<http://click.newsletters.nas.edu/?ju=fe2c157571630475701071&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=> [http://image.newsletters.nas.edu/lib/fef81279746700/i/1/d74c2dd5-6.gif] [http://image.newsletters.nas.edu/FTAF_11.gif]<http://click.newsletters.nas.edu/?ju=fe2b157571630475701072&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=> SEPTEMBER 17, 2012 Reminder to Register for Upcoming Meeting: Exploring Human Genomic Plasticity and Environmental Stressors: Emerging Evidence on Telomeres, Copy Number Variation, and Transposons If you have not already registered for this meeting, please note that registration is NOW OPEN for both on-site and webcast attendees. Our meetings are free and open to the public. Registration and additional information is at http://nas-sites.org/emergingscience/meetings/genomic-plasticity/<http://click.newsletters.nas.edu/?ju=fe2a157571630475701073&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=>. October 4-5, 2012 Thursday 8:30am-5:00pm, Friday 8:30am-12:00noon* Keck Center (Room 100), 500 Fifth Street, NW, Washington D.C. Ready to S-T-R-E-T-C-H Your Thinking about the Human Genome? The human genome is routinely thought of as a static component of the cell, one that is subject to just two fates; to be inherited or to mutate. However, since the completion of the sequencing of the human genome, scientists have been exploring how the genome responds to environmental stressors and chemical exposure. It turns out the genome is much more dynamic than we thought. Genomes have the characteristic of plasticity, which makes it possible to adapt quickly in order to survive changes in environmental conditions. Changes in the genome can have a big impact on human health. The Standing Committee on Emerging Science for Environmental Health Decisions has been exploring factors that influence human health in its workshop series. An earlier forum on Epigenetics (http://nas-sites.org/emergingscience/workshops/epigenetics<http://click.newsletters.nas.edu/?ju=fe29157571630475701074&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=> ) looked at how genes are expressed and silenced in response to environment stressors. Mobile and evolving elements such as telomeres, transposons, and copy number variants are other important factors in understanding the potential effect of our environment on human health. The Genomic Plasticity forum will look beyond random mutation and discuss the fundamental changes in genomic alterations that can contribute to disease and ageing, as well as new technologies and tools to identify and study genome plasticity events. The forum will initiate/foster the exploration of how environmental stressors may impact the genome, by exploring the intersection of mechanisms leading to genomic changes and mechanisms targeted by environmental stressors. SAVE THE DATE! Upcoming Workshops in 2013 January 10-11, 2013: Big Data and Environmental Health: Integrating Research to Advance Discovery (Washington, D.C.) More Information<http://click.newsletters.nas.edu/?ju=fe28157571630475701075&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=> (details to be posted soon) The nation turns to the National Academies-National Academy of Sciences, National Academy of Engineering, Institute of Medicine, and National Research Council-for independent, objective advice on issues that affect people's lives worldwide. Unsubscribe To unsubscribe from this list please go here<http://click.newsletters.nas.edu/?ju=fe27157571630475701076&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=> or reply to this message with "unsubscribe" in the subject line. To manage your subscriptions and account preferences go here<http://click.newsletters.nas.edu/?ju=fe26157571630475701077&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=>. Copyright © 2012. The National Academies. 500 Fifth St. N.W., Washington, D.C. 20001. Privacy Statement<http://click.newsletters.nas.edu/?ju=fe25157571630475701078&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=> [http://image.exct.net/94aebaae-b.jpg] <http://click.newsletters.nas.edu/?ju=fe24157571630475701079&ls=fde717767c6402747c14767d&m=fef81279746700&l=fe961670746706757c&s=fe2710737263027e751c72&jb=ffcf14&t=>