[ascct] Fwd: Expert Insights on In Vitro Alternatives for Drug and Chemical Toxicity Testing

  • From: Kristie Sullivan <KSullivan@xxxxxxxx>
  • To: "ascct@xxxxxxxxxxxxx" <ascct@xxxxxxxxxxxxx>
  • Date: Thu, 7 Aug 2014 11:38:22 -0400

You might be interested in this new journal.

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Contact: Kathryn Ryan
Mary Ann Liebert, Inc., publishers
(914) 740-2100

Expert Insights on In Vitro Alternatives for Drug and Chemical Toxicity Testing

New Rochelle, NY, August 7, 2014—In vitro toxicity testing is rapidly being 
adopted in the pharmaceutical, chemical, and cosmetics industries, for example, 
as an alternative to animal studies to predict adverse health effects of drugs 
and personal care products and the health consequences of environmental 
exposures. An insightful Roundtable Discussion focused on how to apply these 
novel toxicology models to everyday hazard prediction, risk assessment, and 
decision making in industry is published in the preview issue of the new 
journal Applied In Vitro Toxicology, a peer-reviewed publication from Mary Ann 
Liebert, Inc., 
 The article is available free on the Applied In Vitro 

In the Roundtable Discussion "Comments on How to Make the New Vision of 
Toxicity Testing in the 21st Century a 
 Moderator Jim McKim, Editor-in-Chief of Applied In Vitro Toxicology and 
Founder and CEO, IONTOX, LLC, challenges the panelists to present a realistic 
view of how far the field has advanced in implementing the strategy put forth 
in a National Academy of Sciences report to improve toxicity testing.

Panelists Alan Goldberg, Consulting Editor of the Journal, Nicole Kleinstreuer, 
National Toxicology Program Interagency Center for Evaluation of Alternative 
Toxicological Methods (Research Triangle Park, NC), Francois Busquet, Center 
for Alternatives to Animal Testing (Konstanz, Germany), and Melvin Andersen, 
The Hamner Institutes for Health Sciences (RTP, NC), participate in an 
interactive discussion on the use of human cell models combined with 
high-throughput screening methods to test for toxicity, and the complexity of 
applying adverse outcome pathways (AOPs). The conversation covers topics 
ranging from policy issues, challenges related to data interpretation and 
understanding the information gained from in vitro models, the emergence of 
three-dimensional tissue culture models that integrate cells from multiple 
human organs, and the different approaches being used to assess risk from 
high-dose, short-term exposures compared to exposure to lower concentrations of 
a chemical over longer periods of time.

"Improved analytical technologies and improvements in human tissue models will 
allow us to change the animal safety testing paradigm," says Jim McKim.


About the Journal
Applied In Vitro 
 is a new peer-reviewed journal providing the latest research on the 
application of alternative in vitro testing methods for predicting adverse 
effects in the pharmaceutical, chemical, and personal care industries. Led by 
Editor-in-Chief James M. McKim, PhD, DABT, IONTOX, LLC, the Journal addresses 
important issues facing these diverse industries, including regulatory 
requirements; the reduction, refinement, and replacement of animal testing; new 
screening methods; evaluation of new cell and tissue models; and the most 
appropriate methods for assessing safety and satisfying regulatory demands. The 
Journal is published quarterly online with Open Access options and in print. A 
sample issue may be viewed on the Applied In Vitro 

About the Publisher
Mary Ann Liebert, Inc., 
 is a privately held, fully integrated media company known for establishing 
authoritative peer-reviewed journals in promising areas of science and 
biomedical research, including ASSAY and Drug Development Technologies, Human 
Gene Therapy, and OMICS: A Journal of Integrative Biology. Its biotechnology 
trade magazine, Genetic Engineering & Biotechnology News (GEN), was the first 
in its field and is today the industry’s most widely read publication 
worldwide. A complete list of the firm’s 80 journals, books, and newsmagazines 
is available on the Mary Ann Liebert, Inc., 


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  • » [ascct] Fwd: Expert Insights on In Vitro Alternatives for Drug and Chemical Toxicity Testing - Kristie Sullivan