Hi Molly,This is a rare but known potential side effect of immunotherapy. I
have seen great variation in recovery and in symptoms with patients who are
diagnosed with cancer treatment related GBS. In my mind, it is a minimum 2
years ahead of intensive therapeutic management for recovery- PT, OT,
nutrition, psychological and financial. If only folks who are not incredibly
wealthy had access to all of that. My advice to your patient is keep working at
it for years ahead. I have witnessed patients continuing to make gains in
nerologic recovery 5 years or more after diagnosis with non-stop working at it.
-Heidi
On Monday, February 21, 2022, 08:50:56 AM PST, Reynolds Molly
<dmarc-noreply@xxxxxxxxxxxxx> wrote:
Hello,
Has anyone had a patient that was on immunotherapy develop Guillain-Barre? I
have a patient that is on Nivolumab for recurrent esophageal cancer and began
developing stocking-glove distribution neuropathy with progressive weakness.
Eventually he was diagnosed with GB and underwent IVIg infusions. I am now
working with him to learn to walk and do normal ADL’s again. He did not have
any known virus prior to his symptoms. He did receive vaccines in December with
the onset of his symptoms being approximately 4 weeks later. Unfortunately his
immunotherapy was discontinued. Has anyone witnessed this before and if so, did
your patient return to baseline function?
Cheers,
Molly
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