multiplesmyelom: Multiples Myelom

The support group for multiple myeloma and

plasmacytoma has existed since January 2012

and is an open group for all affected persons, relatives

and interested persons.

From time to time, invited speakers will

give lectures on specific topics and answer all

and answer all questions.

Multiple myeloma is a malignant disease of the bone marrow and is

of the bone marrow and results from the

uncontrolled proliferation of degenerate plasma cells.

plasma cells.

The pathologically altered plasma cells

produce antibodies or only fragments of antibodies

of antibodies, the so-called paraproteins.

The production of normal antibodies is suppressed by the

production of paraproteins, and the patient becomes more

patient becomes more susceptible to infection.

In the bone marrow, the proliferation of myeloma cells

myeloma cells leads to increased stimulation of osteoclasts.

of osteoclasts. These are cells that can

bone substance.

This leads to an increased release of calcium.

If large quantities of paraproteins are

the protein content of the blood can increase considerably.

increase. Because part of the protein is excreted by the kidneys, it can

excreted by the kidneys, it can clog the renal tubules and

and impair their function.

Multiple myeloma can progress for years without any noticeable

noticeable signs of the disease. The effects of the

effects of the disease described here usually

usually appear only after a longer

course of the disease.

Possible symptoms of

Myeloma disease:

Bone pain and fractures due to the

loss of bone substance

Signs of anemia, such as lassitude,

lack of drive, shortness of breath during exertion, irritability

or headaches (very common)

Susceptibility to infections with frequently recurring,

persistent infections (less frequent)

Weight gain due to storage of

fluid in body tissues may be a sign of

kidney function impairment

Calcium elevation in the blood may result in

Kidney damage, fatigue, confusion,

cardiac arrhythmias, nausea and vomiting.

occur. (hypercalcemia; very rare)National Multiple Myeloma Association

The diagnosis of multiple myeloma or

plasmocytoma triggers shock, fear and helplessness in those affected.

and perplexity.

What kind of disease it is and how it can be

and how it can be treated are the central

questions that arise.

Why multiple myeloma develops is still largely unknown.

largely unexplained. It is also a cancer

is a cancer that cannot yet be cured.

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