[tri-med] Re: tri children and reproduction

----- Original Message ----- 
From: "Meierlaw"
> Shelby is in EI because she was born at 5 months and weighed only around 1
> pound - there are many premature babies placed into EI.  She was tested
for
> T-18 at birth and she is NOT an 18.

Yes - very possible.........
it sounds like mum is a partial partial, that is that she has an extra part
of one of the arms as opposed to a full p or q arm - that would be why she
is doing so well. Or maybe she is a mosaic partial like US Alex. As I said
way too many variables to even hazard a guess. It would be easier to just
get out chi squares and start calculating.

But its very possible to have a typical child when one of the parents has
mosaicism or a partial trisomy.

And thats why trisomy CAN be hereditary, even in full trisomy, though that
scenario is usually where one of the parents is mosaic T-18. Its rare, very,
very rare, (so no one panic PLEASE) but its possible, can and does happen.
Well documented in the literature - and I have met a few folk in person as
well over the years. We actually had a mum on the list (deep lurk) who was
herself a mosaic T-18.

And just to reassure everyone I will say it again - its RARE for FULL T-18
to be heredtiary!!!!!!!!!! Even rare for it to happen unexpectedly. Think of
the odds. Less than 1% of all T-18'ers are mosaicers. The odds of a mosaicer
being so high functioning and without the medical problems that would draw
attention to anything to warrant chromosome testing until the reproductive
years is so high that most geneticists disregard the possibility. Thats why
they don't routinely recommend that parents be tested. Some paranoid folk
like myself insist on the peace of mind in testing :-) but its personal
choice, and if you are anxious then request testing.

The fact that it does happen stands out in our minds against the background
of the number where it doesn't which is far, far greater.

The hope for Alex in my mind (because its quite possible for my mind to see
him fathering children one day) is in all the new genetics and in vitro
techniques. Still scares me totally silly, can't imagine my baby having
babies. But then I can't imagine my typical daughters having babies - and I
already have grandchildren!!! (2 and another on the way - Virginia not
Amanda, Jocelyn :-))). I also can't imagine ME making those sorts of
choices, let alone Alex. But one day he will............... I just hope he
does as well as Shelby.

I have not lost my mind - it's backed up on disk somewhere.
-- Unknown

Keep Looking For Rainbows!!
   _--_|\
 /Karen \
 \ _.--._ /
          v Karen, Mum to Alex (8 years, T-18 Mosaic)
http://members.optushome.com.au/karens


                  Building ___ooOOoo__ Rainbows
                       www.trisomyonline.org
                  Families Helping Families On-line

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