[tri-med] Fw: Liver Cancer

Loren,
This is the response from John (I did delete a paragraph of personal mail
for me from the end of the mail otherwise it is as is)

----- Original Message -----
From: John Carey

Karen,
 I am aware of 8 cases of trisomy 18 with hepatoblastoma ( 2 were mosaic)-
the age range was 4 mos to 3 yrs ( take a peak at my professional newletter
that came out about a year ago- it is on www trisomy.org) . I am not aware
of Zantac causing "benign liver tumors" -I would have to look that up. The
possibilty of some predisposition in trisomy 18 is so mind bogling that I
would like to ask my liver cancer experts whether there is any theoretical
reason why Zantac could cause hepatoblastoma in a child who may be at risk,
i.e. having trisomy 18. I'll check the published reports ( they are in my
briefcase at my othe office) to see if any kids were on Zantac -of note 3 of
the cases are Japanese.

                  Building ___ooOOoo__ Rainbows
                       www.trisomyonline.org
                  Families Helping Families On-line

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