[statisticalgenetics] Journal club - 10:15am 14/06/2012

  • From: Gibran Hemani <g.hemani@xxxxxxxxx>
  • To: "statisticalgenetics@xxxxxxxxxxxxx" <statisticalgenetics@xxxxxxxxxxxxx>
  • Date: Fri, 8 Jun 2012 06:23:41 +0000

Dear all

Next week Hong Lee will be presenting the following paper:

"Power in GWAS: lifting the curse of the clinical cut-off"
van der Sluis et al
Molecular Psychiatry 2012 aop doi:10.1038/mp.2012.65

It can be downloaded here:
https://dl.dropbox.com/u/4674736/vanderSuis2012.pdf


Some additional info from Hong:

"The paper shows that a better use of phenotypes substantially increases the 
power of GWAS. However, the paper did not really consider sampling strategy and 
design which may be important as well in practice. In addition to reviewing the 
paper, I will additionally show some results and discussions based on theory 
and simulation."


As usual:

Time: 10:15am Thursday 14th June
Place: 7th Floor Seminar Room, QBI (building #79)


All the best

Gib

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