[ppi] [ppiindia] Single protein key to memory

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Dulu, tahun 1970an Prof. Dr. Wahyudi Wisaksono dari
Lemigas dengan teamnya yang terdiri dari berbagai
kalangan mengadakan penelitian 'Single Cell Protein'
menggunakan minyak mentah (crude oil) sebagai bahan
dasarnya.  Tapi proyek ini gagal total, setelah
kedapatan bahwa bahan dari minyak mentah bersifat
carcinogenic atau penimbul kanker.

Sekarang peneliti di Cornell University menemukan
bahwa single protein penting bagi daya mengingat. 

Salam,
RM


Single protein key to memory

The preservation of our memories may depend upon the
actions of a single protein, according to a new study
published in the current issue of the journal Science.

WILLIAM HATHAWAY
LA TIMES


The preservation of our memories may depend upon the
actions of a single protein, according to a new study
published in the current issue of the journal Science.
The protein appears to chemically alter neurons and
boost their ability to communicate with one another. 

Scientists long have sought to describe all the
biochemical events that lead to formation of long-term
memories -- those that can be recalled after a day or
more. 

Researchers at Cornell University and co-authors of
the Science paper had previously discovered the
chemical recipe that produces a protein called mBDNF,
or mature brain-derived neurotrophic factor. They
believe the protein is a key player in the formation
of memories. 

In the Science study, scientists at the National
Institute of Child Health and Human Development, a
part of the National Institutes of Health, wanted to
see whether the protein could produce a burst of
neural activity known as L-LTP, or late long-term
potentiation, which occurs during memory formation. 

Working with tissue taken from mice brains, the
scientists found that mBDNF was a crucial ingredient
in producing L-LTP in the hippocampus, a section of
the brain crucial to the formation of memories. The
work with mBDNF might one day help people with
learning and memory disorders, the researchers said. 





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