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MEDICAL: CONDITIONS: OBESITY :
MEDICAL: RESEARCH :
MEDICAL: PHARMACY PHARMACEUTICAL PHARMACOLOGY: DRUGS :
Researchers are Creating a Drug to Replicate Exercise
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Researchers are Creating a Drug to Replicate Exercise
Friday 24 March 2017
Benedict Jephcote
Diabetes.co.uk
https://diabetes.co.uk/news/2017/mar/
researchers-are-creating-a-drug-to-replicate-exercise-95821409.html
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A shorter URL for the above link:
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http://tinyurl.com/lqtjcdn
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Researchers have announced they are working on creating a drug which they
hope will capture the benefits of exercise in pill form.
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The team from Saint Louis University want to build on previous work in a
bid to create a tablet which will help ease the burden of type 2 diabetes.
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Co-researcher Dr Thomas Burris, chair of pharmacology and physiology at
the university, has previously developed a drug which targets the protein
called REV-ERB, which appears to mimic exercise.
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snip
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Dr Burris said: "If you exercise, it's effectively a treatment for
diabetes and obesity as you increase the metabolic rate of muscle. You
develop a more efficient muscle. That's what you get from exercise. You
develop more endurance and that is good for your metabolic function.
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"Our drug compounds are doing similar things. They make muscles look like
they're exercising, turning on the genes that get activated during
exercise, even if no exercise is happening."
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Although it is unlikely a drug will ever be able to fully replicate the
benefits of exercise, Dr Burris work could copy the way activity affects
muscle metabolism.
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The complete article may be read at the URL above.
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Sincerely,
David Dillard
Temple University
(215) 204 - 4584
jwne@xxxxxxxxxx
http://workface.com/e/daviddillard
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