Hi: I've done a couple of assemblies on the same reads using both programs. Around half million ESTs reads. Newbler is much faster than mira, but the newbler result is awful. mira gives reasonable contigs, but newbler does really stupid things. So, I just wanted to give to you two thumbs up, you're doing a great job! Regards, -- Jose M. Blanca Postigo Instituto Universitario de Conservacion y Mejora de la Agrodiversidad Valenciana (COMAV) Universidad Politecnica de Valencia (UPV) Edificio CPI (Ciudad Politecnica de la Innovacion), 8E 46022 Valencia (SPAIN) Tlf.:+34-96-3877000 (ext 88473) -- You have received this mail because you are subscribed to the mira_talk mailing list. For information on how to subscribe or unsubscribe, please visit http://www.chevreux.org/mira_mailinglists.html