[mira_talk] Re: extremely high illumina coverage

  • From: Bastien Chevreux <bach@xxxxxxxxxxxx>
  • To: mira_talk@xxxxxxxxxxxxx
  • Date: Tue, 18 Oct 2011 23:20:04 +0200

On Oct 18, 2011, at 22:27 , Nestor Zaburannyi wrote:
> Thanks  for  the answer. And if it is GC-rich? I am reluctant of using
> more  than  100x,  because of people here saying it is not good. Also,
> because MIRA gets very slow.

GC rich data make the appearance of the GGCxG motif related sequencing error 
more frequent. There is less sequencing data per se present and it has more 
errors ... this combined with clipping may lead to zero assembly coverage, even 
at higher raw coverages.

B.
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