[mira_talk] MIRA 3 release candidate 1

Dear all,

well, I finally decided to go for a 3 as major version number ... even if it's 
still labeled "release candidate" :-)

There have been some major speed optimisations since 2.9.46 which should bring 
down assembly times in projects with several millions of reads (be they 
Sanger, 454 or Solexa). At least it does so for my projects. Memory management 
for Solexa reads (and unclipped 454 reads) has been improved and uses less 
memory.

Furthermore, hybrid assembly with Solexa reads has been smoothed out and fully 
integrated into the usual command line scheme. Before (since late 2.9.37 
versions) one had to set quite a bunch of parameters correctly by hand, now 
the quick switch should perform almost everything automagically. And it's a 
lot faster than in previous versions. E.g. de-novo in 5 passes with 810k 454 
and 3.3m Solexa in roundabout 12 hours instead of 1.5 days.

A number of additional convenience changes, bug fixes and small features are 
also present like, e.g., FASTQ is now understood by MIRA.

The new version has just been put online for download (sources and binaries): 
http://www.chevreux.org/mira_downloads.html

Regards,
  Bastien


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