[mira_talk] Re: Call for testing: MIRA 3.2.1.5

  • From: Ganga Jeena <ganga.jeena@xxxxxxxxx>
  • To: mira_talk@xxxxxxxxxxxxx
  • Date: Thu, 10 Feb 2011 11:11:28 +0530

Dear Sir,
would this be as effective for genome assembly too................??
Regards,
Ganga Jeena

On Wed, Feb 9, 2011 at 2:48 AM, Bastien Chevreux <bach@xxxxxxxxxxxx> wrote:

> Dear all,
>
> development of MIRA is happily progressing and changes to my source
> management
> makes it now easier to make available snapshots which contain most changes
> that will make their way into the next stable release.
>
> These snapshots will not contain the latest bleeding edge new developments
> I
> am currently working on / testing out, so they should be relatively stable
> as
> they most of the time went through a couple of projects on my home machine
> already.
>
> So, version 3.2.1.5 begins and you'll find it at
>
>  https://sourceforge.net/projects/mira-assembler/files/MIRA/development/
>
> Main development since 3.2.1:
>
> - people working on *large* EST / RNASeq projects will be happy to hear
> that
>  data sets with millions of reads (Sanger, 454 or Solexa) will now finish
> much
>  quicker in de-novo mode. E.g., 10  million Solexa 100 bp goes down from
> ~10
>  days to just around 2 days.
> - genome mappings with tens of millions of reads are now also a lot
> quicker.
>  E.g.: 1 day instead of almost 3 for a project with 33 million Solexas.
> - mapping assemblies with lots of backbone sequences also improved
> noticeably
>  (factor 3 or 4 iirc)
> - memory needs also substantially went down. E.g.: in Solexa transcriptome
> 10m
>  reads  @ 100bp with quite some ploidy, an internal data structure shrank
>  from ~11.5 GiB to ~1 GiB.
> - compilation on OSX should now be a breeze
> - recognition of non-standard BOOST library installs should be much better
> - lots of smaller bugfixes and tweaks to ease my life during assemblies
>
> Feedback appreciated.
>
> Have fun trying it out,
>  Bastien
>
> PS: oh yeah ... and from now on, pre-built OSX 64 bit binaries are part of
> the
> deliveries and should run flawlessly on every machine >= OSX 10.5 and a 64
> bit
> CPU (for 32 bit versions ... compile yourself :-)
>
> --
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