[mira_talk] Re: Assembling 454 and Solexa mate-pair data - rethinking ...
- From: Bastien Chevreux <bach@xxxxxxxxxxxx>
- To: mira_talk@xxxxxxxxxxxxx
- Date: Thu, 10 Sep 2009 17:09:36 +0200
On Donnerstag 10 September 2009 Martin A. Hansen wrote:
> So, why are qualities so important? If you have enough sequence it should
> level out?
The "non-perfect-repeat" detection routines heavily rely on qualities to tag
bases that aid to discern the different repeats. The base calling algorithms
also take qualities into consideration when confronted to unsure situations.
Plus a few other places where qualities do matter quite a lot :-)
B.
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