Failing requests

Hi Folks.
 
We've had ISA running successfully (gasp!) for about 5 months now.
I keep perfmon running on it and sometimes, we'll see a lot of failing
requests/sec.
I see a maximum of 30 requests/sec and a maximum of 6 failing requests/sec.
They don't coincide though.
Is this normal?
If not, how can I remedy this?
By the way, on the client side, this is seen as an error "64 - Host not
available Internet Security and Acceleration Server", "The gateway has lost
the connection...."
 
Your help is very much appreciated.
Thank you.
 
- Umesh

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